. . A pathologic fracture is a fracture caused by a disease or disorder leading to weakness of the bone. The bony lesion will often take on a moth-eaten appearance. Some of the most common causes are osteoporosis, malignancy lesions, infection, benign bone lesions, osteogenesis imperfecta and others.
The most common primary malignancies that metastasize to the bone are the :
breast
lung
kidney
prostate
thyroid
