Finding a STEMI in the presence of the Left Bundle Branch Block (LBBB)

– Vernon R. Stanley, MD, PhD | (C) 2020 Renewed 

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You have been requested to interpret the 12-lead tracing below with a particular focus of uncovering acute myocardial ischemia/infarction.


LBBB with Primary T-waves noted.  This is sometimes suspicious of myocardial disease.

ST-T changes Leads V1, V2 probably pseudo-infarction changes (cannot rule out ischemia /infarction).

Clinical correlation recommended and comparison with old tracing.


1.  Review of the criteria of the classic LBBB.

2.  Primary and Secondary T-wave changes of the LBBB.

3.  Utilization of the computer interpretation.

The criteria of the classic LBBB is as follows:

Triad of the LBBB

  1. | QRS | > or = 0.12 sec.
  2. Lead V6 or V5 or V4 RSR’ complex (slur or notch).
  3. Lead I is all upright with slur or notch.

Notice that this Case Study tracing does indeed satisfy the TRIAD of the LBBB.


Please scroll up to this Case Study tracing and note that I have circled, magnified and color-labeled Leads I, II and V6.  In particular, notice the terminal portion of the QRS complex – each one of these areas is positive.  Now notice the T-wave’s polarity, i.e. each of the T-waves is also POSITIVE (UPRIGHT).

This polarity of



is described as PRIMARY T-WAVE changes or concordance of the QRS-T waves.


The T-wave is directed in the same direction as the terminal portion of the QRS complex.  For example

if the terminal portion of the QRS complex is POSITIVE….the T-wave is UPRIGHT (POSITIVE)
If the terminal portion of the QRS complex is NEGATIVE…the T-wave is INVERTED (NEGATIVE).

These are described as PRIMARY T-WAVES or concordance of the QRS-T.  This clinically is uncommon and indeed represents suspicion of myocardial disease such as myocardial ischemia.  Primary T-waves basically represent a red flag and serve as a guide and warning to be even more diligent with your clinical correlation, cardiac markers and comparison with the old 12-Lead tracing.


If the terminal portion of the QRS complex is POSITIVE…the T-wave is INVERTED (NEGATIVE).

If the terminal portion of the QRS complex is NEGATIVE…the T-wave is UPRIGHT (POSITIVE).

These QRS-T polarity correlations are called SECONDARY T-waves or discordance of the QRS-T.  It is the most common finding in the LBBB and unlike the PRIMARY T-waves does NOT suggest ischemia/infarction.


PRIMARY T-WAVES in the LBBB is an uncommon finding and is sometimes indicative of disease such as myocardial ischemia.  The LBBB is the greatest booby trap of electrocardiography and its distortion of the waveform makes it extremely difficult to recognize ECG changes of the Acute MI or ischemia.  Indeed, the changes observed are usually pseudoinfarction/ischemia changes, these common findings are as follows [Be aware of the diagnostic STEMI changes of the Sgarbossa Criteria]:

LEADS……………………….COMMON FINDINGS (usually pseudoinfarction/ischemia)

V1, V2, V3………………….Significantly wide Q-waves

V1, V2, V3………………….ST elevation concave down

V1, V2, V3………………….Peaked T-waves

I, avL, V6, V5, V4………..ST depression and/or T-wave inversion


You can diagnose the acute STEMI if the ECG satisfies the Sgarbossa Criteria. We will revisit this phenomenon in a later posting.


It is well agreed that the practitioner should not make treatment and disposition decisions based on the computer interpretation of the 12-Lead.  The computer often misinterprets, overreads and underreads.  This is especially true in the area of ST-T analysis.  My advice is simple:

The computer interpretation is valuable as a second opinion but the most important first opinion is that of the human brain ——– yours.  The analysis of the ST-T changes of the cardiogram is fraught with mimics, masks, booby traps and pseudopatterns.  The computer software is often unable to systematically defuse this mine field and may lead you to believe that the tracing is an acute MI (or not) with catastrophic results associated with the inappropriate treatment.

Please scroll back up to this Case Study tracing and notice I have placed an ellipse and magnified the text of the computer measurements.  These measurements will serve as a quick reference and they are USUALLY CORRECT.  You should especially establish the habit of noting the following measurements:

Voltage criteria for Hypertrophy

Ventricular Rate


  • PR interval
  • | QRS |
  • QT/QTc


QRS-ST analysis

  • R-wave progression
  • Transition Zone

©2017, 2023 Renewed Vernon R. Stanley, MD, PhD.  All Rights Reserved

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